lunedì 12 dicembre 2016

5° meeting del NBG

Le neuroscienze nell'area napoletana

15 Dicembre 2016


CEINGE Biotecnologie Avanzate s.c. a r.l. 

Via Gaetano Salvatore 486 (ex-Via Comunale Margherita), 
80131 Napoli, Italia



Comitato scientifico
 Ennio Del Giudice (UNINA), L. Annunziato (UNINA), A. Usiello (CEINGE), Carla Lucini (UNINA), Elia Di Schiavi (IBBR, CNR), Mauro Cataldi (UNINA)





PROGRAMMA

Introduzione: presentazione dell'NBG          09.00 – 09.15

PRIMA SESSIONE  Chair: F. Salvatore (CEINGE, UNINA), E. Del Giudice (UNINA)

MOLECULAR NEUROBIOLOGY 09.15 – 10.30
Imperatore R. (IBC,CNR)
Orexin, endocannabinoid and leptin interaction affects hypothalamic Tau phosphorilation.
Indrieri A. (TIGEM) 
Synthetic long non-coding RNAs [SINEUPs] rescue defective gene expression in vivo.
Giuditta A. (UNINA)
Brain metabolic DNA in memory processing and genome turnover.
De Biase D. (UNINA) 
Lipofuscin storage and autophagy dysregulation in aged bovine brain.
D’Angelo L. (UNINA) 
Nothobranchius furzeri: a model for studying neurobiology of ageing in the fast lane.

NEURODEVELOPMENT/NEUROPHYSIOLOGY        10.30 – 11.45
D’Aniello S. (SZN)
Novel implications in Neurotrophins during the development of the nervous system
Dubbioso R. (UNINA)
Center-surround organization of the human sensorimotor system.
Esposito M.(SUN)
Developmental coordination disorder in children and sleep architecture: a case-control study.
Intartaglia D. (TIGEM)
MIR-204/211 in eye development and disease: an intricate relationship
Vitiello G. (UNINA)
An integrated clinical and genetic approach to corpus callosum abnormalities.

EPILEPSY AND EPILEPTIC DISORDERS   11.45 – 13.15
Miceli F. (UNINA)
Pathogenetic mechanisms for early-onset epileptic encephalopathy caused by mutations in Kv7.2 voltage-gated K+ channels.
Di Giaimo R. (UNINA)
Molecular and cellular role of cystatin B in cerebral cortex development and in the etiopathogenesis of EPM1.
Poeta L. (IGB, CNR)
Histone methylation-demethylation defects in forms of Intellectual Disability and Refractory Epilepsy: Analysis of disease-related pathways in in vitro and in vivo models.
Terrone G. (UNINA)
A novel combination of drugs with antioxidant effects prevents progression of epilepsy in a rat model of acquired epileptogenesis.
Cataldi M. (UNINA)
Carbachol-induced network oscillations in an in vitro limbic system brain slice.
Viggiano A. (UNISA)
Ketogenic diet prevents neuronal firing increase within the substantia nigra during pentylenetetrazole-induced seizure in rats.

BREAK: 13.15 – 14.00

SECONDA SESSIONE Chair: L. Annunziato (UNINA), A. Usiello (CEINGE, UNINA)

PSYCHIATRIC DISORDERS 14.00 – 15.30
Buonaguro E.F. (UNINA)
Genetic-driven partial reduction of dopamine transporter function recapitulates ADHD- but not schizophrenia-related phenotypes.
Catone G. (SUN)
Psychotic like experiences in help seeking adolescents and relationship with bullying victimization.
De Risi M. (TIGEM)
Autism-like behavioral symptoms are associated to striatal dopamine system dysregulation in mucopolysaccharidosis type III-A
Cappuccio G. (UNINA)
A pseudogene increasing LRFN5 expression in a patient with 14q21.2 deletion and autism
Errico F. (CEINGE)
Potential involvement of the NMDA receptor agonist D-aspartate in schizophrenia.
Guida F. (SUN)
Lactobacillus casei DG restores dysbiosis-induced gut inflammation, depressive behaviour and recognition memory deficit associated with physiological alterations in the hippocampus

NEURODEGENERATIVE DISORDERS   15.30 – 17.15
Colarusso A. (UNINA)
Towards the exploitation of CNF1 toxin as a potential treatment of some central nervous system diseases.
Penna E. (UNINA)
Local synthesis of APP in synaptosomal fraction from brain of Alzheimer's disease animal model
Di Schiavi E. (IBBR, CNR)
Identification of neuroprotective molecules using a C. elegans model of Spinal Muscular Atrophy
Pulcrano S. (IGB, CNR)
Dopaminergic differentiation using microRNAs.
Sorrentino N.C. (TIGEM)
New therapeutic approaches to treat CNS pathology in lysosomal storage disorders
Saracino D. (SUN)
A cluster of progranulin C157KfsX97 mutations in Southern Italy: clinical characterisation and genetic correlations.
Gallo V. (UNINA)
Neurological abnormalities in a SCID patient carrying mutation of  ARTEMIS, ADA and ERCC6 genes identified through Next Generation Sequencing

NEUROIMAGING/BIOMARKERS 17.15 – 18.15
Tarallo A. (UNINA)
Micro-RNA as biomarkers in Pompe Disease.
Mazio F. (SUN)
Encephalic volumetric alterations in long-term survivor Acute Lymphoblastic Leukemia patients identified with VBM analysis.
Tedeschi E. (UNINA)
A model of possible applications of advanced MRI techniques in the field of inherited metabolic disorders: Fabry disease.
Vallelunga A. (UNISA)
Serum MIR-148b as a potential biomarker for Multiple System Atrophy:a pilot study.

Concluding remarks:  E. Del Giudice   18.15 – 18.30